Stress Ulcer is not caused by the “every day stress” a person undergoes in his work or family. It rather is the manifestation of peptic ulcer because of a prolonged and serious illness. Patients who experience prolonged stay in Intensive Care Unit (ICU) typically get stress ulcers. That does not essentially mean that the facilities in the ICU have caused “Stress Ulcer”. It is because a patient undergoes prolonged stay in ICU because of the seriousness of the illness and whose health is at stake. Patients who have met with accident and have lost lot of blood also get stress ulcer when they are hospitalized. Medications also play a role in getting stress ulcer.